Curry and Cancer

Curry and CancerIt is estimated that tumors start at around the age of 20, yet detection of cancer is normally around the age of 50 or later, thus it takes cancer decades to incubate. Why does it take so long? Recent studies indicate that in any given type of cancer hundreds of different genes must be modified to change a normal cell into a cancer cell. Although cancers are characterized by the dysregulation of cell signaling pathways at multiple steps, most current anticancer therapies involve the modulation of a single target. Chemotherapy has gotten incredibly specific, but the ineffectiveness, lack of safety, and high cost of these monotargeted therapies has led to real disappointment, and drug companies are now trying to develop chemo drugs that take a more multitargeted approach. As a result, many pharmaceutical companies are increasingly interested in developing multitargeted therapies.

Many plant-based products, however, accomplish multitargeting naturally and, in addition, are inexpensive and safe compared to drugs. However, because drug companies are not usually able to secure intellectual property rights to plants, the development of plant-based anticancer therapies has not been prioritized. They may work, they may work better for all we know; they may be safer—they may actually be safe, period.

If you were going to choose one plant-based product to start testing, one might choose curcumin, the pigment in the spice turmeric, the reason curry powder looks yellow.

Well before you start throwing money at research, you might want to start asking some basic questions, like “Do populations that eat a lot of turmeric have lower cancer rates?” The incidence of cancer does appear to be significantly lower in regions where turmeric is heavily consumed. Population-based data indicate that some extremely common cancers in the Western world are much less prevalent in regions where turmeric is widely consumed in the diet. For example, overall cancer rates are much lower in India than in western countries.

Much lower. U.S. men get 23 times more prostate cancer than men in India. Americans get between 8 and 14 times the rate of melanoma, 10 to 11 times more colorectal cancer, 9 times more endometrial cancer, 7 to 17 times more lung cancer, 7 to 8 times more bladder cancer, 5 times more breast cancer, and 9 to12 times more kidney cancer. And this is not like 5, 10, or 20 percent more, but times more. So hundreds of percent more breast cancer, thousands of percent more prostate cancer, differences even greater than some of those found in the China Study.

Because Indians account for one-sixth of the world’s population, and have some of the highest spice consumption in the world, epidemiologic studies in this country have great potential for improving our understanding of the relationship between diet and cancer. Of course it may not be the spices.

Several dietary factors may contribute to the low overall rate of cancer in India. Among them are a relatively low intake of meat and a mostly plant-based diet in addition to the high intake of spices. Forty percent of Indians are vegetarians, and even the ones that do eat meat don’t eat a lot. And it’s not only what they don’t eat, but what they do. India is one of the largest producers and consumers of fresh fruits and vegetables, and they eat a lot of pulses, meaning legumes—beans, chickpeas, and lentils. And it’s not just turmeric, they eat a wide variety of spices that constitute, by weight, the most antioxidant-packed class of foods in the world.

Population studies can’t prove a correlation between dietary turmeric and decreased cancer risk, but they can certainly inspire a bunch of research. So far, curcumin has been tested against a variety of human cancers, including colorectal cancer, pancreatic cancer, breast, prostate, multiple myeloma, lung cancer, and head and neck cancer, for both prevention and treatment. We’ll look at some of this research, next.

Doctor’s Note

This is the first in a three-part video series on turmeric and cancer. Once they’re up, make sure you check out the next two videos: Carcinogen Blocking Effects of Turmeric Curcumin and Turmeric Curcumin Reprogramming Cancer Cell Death. You can subscribe to get email alerts when they are up by clicking here.

I’m working on another dozen or so videos on this amazing spice. This is what I have so far:

Amla, dried Indian gooseberry powder, is another promising dietary addition:

I add amla to my Pink Juice with Green Foam recipe. Not all natural products from India are safe, though. See, for example, my video Some Ayurvedic Medicine Worse than Lead Paint Exposure.

More on the antioxidant concentration in spices in general in Antioxidants in a Pinch. Why do antioxidants matter? See Food Antioxidants and Cancer and Food Antioxidants, Stroke, and Heart Disease.

Which fruits and vegetables might be best? See #1 Anticancer Vegetable and Best Fruits for Cancer Prevention.

Featured Photo Source: FourWinds10

Michael Greger M.D.About Michael Greger M.D.Michael Greger, M.D., is a physician, author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United States.

4 Things To Help Prevent Most Disease

White House Garden Goes Organic For Healthy LifestyleBy: Dr. Michael Greger, Director of Public Health and Animal Agriculture at the Humane Society of the United States.

Though I was trained as a general practitioner, my chosen specialty is lifestyle medicine. Most of the reasons we go see our doctors are for diseases that could have been prevented. But lifestyle medicine is not just about preventing chronic disease—it’s also about treating it. And not just treating the disease, but treating the causes of disease.

If people just did four simple things
Stop Smoking For Your Health

#1 No Smoking

The Obama Family Exercising

#2 Exercise A Half Hour A Day

Michelle Obama Shopping At A Farmers Market For Fruits & Vegetables

#3 Eat a Diet That Emphasizes Whole Plant Foods

Eat Diet That Emphasizes Whole Plant Foods

#4 And Not Become Obese

they may prevent most cases of diabetes and heart attacks, half of strokes, and a third of cancers. Even modest changes may be more effective in reducing cardiovascular disease, high blood pressure, heart failure, stroke, cancer, diabetes, and all-cause mortality than almost any other medical intervention.

The key difference between conventional medicine and lifestyle medicine is instead of just treating risk factors, we treat the underlying causes of disease, as Drs. Hyman, Ornish, and Roizen describe in their landmark editorial Lifestyle medicine: treating the causes of disease. Doctors typically treat “risk factors” for disease by giving a lifetime’s worth of medications to lower high blood pressure, elevated blood sugar, and high cholesterol. But think about it: high blood pressure is just a symptom of diseased and dysfunctional arteries. We can artificially lower blood pressure with drugs, but that’s not treating the underlying cause. To treat the underlying cause, we need things like diet and exercise, the “penicillin” of lifestyle medicine (See Lifestyle Medicine: Treating the Causes of Disease).

As Dr. Dean Ornish is fond of saying, disregarding the underlying causes and treating only risk factors is somewhat like mopping up the floor around an over-flowing sink instead of just turning off the faucet, which is why medications usually have to be taken for a lifetime. As Dr. Denis Burkitt described, “if a floor is flooded as a result of a dripping tap, it is of little use to mop up the floor unless the tap is turned off. The water from the tap represents the cost of disease, and the flooded floor represents the diseases filling our hospital beds. Medical students learn far more about methods of floor mopping than about turning off taps, and doctors who are specialists in mops and brushes can earn infinitely more money than those dedicated to shutting off taps.” And the drug companies are more than happy to sell rolls of paper towels so patients can buy a new roll every day for the rest of their lives. Paraphrasing poet, Ogden Nash, modern medicine is making great progress, but is headed in the wrong direction.

When the underlying lifestyle causes are addressed, patients often are able to stop taking medication or avoid surgery. We spend billions cracking patients’ chests open, but only rarely does it actually prolong anyone’s life. Instead of surgery, why not instead wipe out at least 90% of heart disease through prevention? Heart disease accounts for more premature deaths than any other illness and is almost completely preventable simply by changing diet and lifestyle, and the same dietary changes required can prevent or reverse many other chronic diseases as well.

So why don’t more doctors do it?

One reason is doctors don’t get paid to do it. No one profits from lifestyle medicine, so it is not part of medical education or practice. Presently, physicians lack training and financial incentives, so they continue to do what they know how to do: prescribe medication and perform surgery.

After Dean Ornish proved you could open up arteries and reverse our number one cause of death, heart disease, with just a plant-based diet and other healthy lifestyle changes (see Resuscitating Medicare and Our Number One Killer Can Be Stopped), he thought that his studies would have a meaningful effect on the practice of mainstream cardiology. After all, he had found a cure for our #1 killer! But, he admits, he was mistaken. “Physician reimbursement,” he realized, “is a much more powerful determinant of medical practice than research.”

Reimbursement over research. Salary over science. Wealth over health. Not a very flattering portrayal of the healing profession. But if doctors won’t do it without getting paid, let’s get them paid.

So Dr. Ornish went to Washington. He argued that if we train and pay for doctors to learn how to help patients address the real causes of disease with lifestyle medicine and not just treat disease risk factors we could save trillions of dollars. And that’s considering only heart disease, diabetes, prostate and breast cancer. The Take Back Your Health Act was introduced in the U.S. Senate to induce doctors to learn and practice lifestyle medicine, not only because it works better, but because they will be paid to do it. Sadly, the bill died, just like millions of Americans will continue to do with reversible chronic diseases.

By treating the root causes of diseases with plants not pills, we can also avoid the adverse side effects of prescription drugs that kill more than 100,000 Americans every year, effectively making doctors a leading cause of death in the United States. See One in a Thousand: Ending the Heart Disease Epidemic and my live presentation Uprooting the Leading Causes of Death.

For those surprised that policy makers wouldn’t support such a common sense notion as preventive health, check out my video The McGovern Report. What about medical associations? Medical Associations Oppose Bill to Mandate Nutrition Training.

There is another reason that may explain why the medical profession remains so entrenched. See my video The Tomato Effect.

-Michael Greger, M.D.

PS: If you haven’t yet, you can subscribe to my free videos here and watch my live year-in-review presentations More Than an Apple a Day and From Table to Able.

Michael Greger M.D.About Michael Greger M.D.
Michael Greger, M.D., is a physician, author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United States.

Video Sources

Photo Sources: Obama Eating Fruit, Michelle Obama Shopping, Obama Family Exercising

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