How to Block Breast Cancer’s Estrogen-Producing Enzymes

The vast majority of breast cancers start out “hormone-dependent,” meaning the primary human estrogen, called “estradiol plays a crucial role in [breast cancer] development and progression.” That’s one of the reasons why soy food consumption appears so protective against breast cancer—because soy phytoestrogens, like genistein, act as estrogen-blockers. They block the binding of estrogens, like estradiol, to breast cancer cells.

But, wait a second. “The majority of breast cancers occur [after menopause], when the ovaries have [stopped producing estrogen].” What’s the point of eating estrogen blockers if there’s no estrogen to block? It turns out the breast cancer tumors themselves produce their own estrogen from scratch to fuel their own growth.

Estrogens may be formed in breast tumors by multiple pathways. The breast cancer takes cholesterol, and, using the aromatase enzyme, or two hydroxysteroid dehydrogenase enzymes, produces its own estrogen.

So, there’s two ways to stop breast cancer. One is to use “antiestrogens,” estrogen-blockers, like the soy phytoestrogens, or “the anti-estrogen [drug] tamoxifen…However, another way to block estradiol is by using anti-enzymes” to prevent the breast cancer from making all the estrogen in the first place.

And, indeed, there are a variety of anti-aromatase drugs in current use. In fact, inhibiting the estrogen production has been shown to be “more effective” than just trying to block the effects of the estrogen—”suggesting that the inhibition of estrogen synthesis is clinically very important for the treatment of estrogen-dependent breast cancer.” It turns out soy phytoestrogens can do both.

Using ovary cells taken from women undergoing in vitro fertilization, soy phytoestrogens were found to reduce the expression of the aromatase enzyme. What about in breast cancer cells, though? Breast cancer cells, too—not only suppressing aromatase activity, but the other estrogen-producing enzyme, too.

But, this is in a petri dish. Does soy suppress estrogen production in people too Well, circulating estrogen levels appear significantly lower in Japanese women than American white women. And, Japan does have the highest per capita soy food consumption. But, you don’t know it’s the soy until you put it to the test. Japanese women were randomized to add soymilk to their diet—or not—for a few months. Estrogen levels did seem to drop about a quarter in the soymilk-supplemented group. Interestingly, when they tried the same experiment in men, they got similar results: a significant drop in female hormone levels, with no change in testosterone levels.

These results, though, are in Japanese men and women that were already consuming soy in their baseline diet. So, it’s really just looking at “higher versus lower…soy intake.”

What happens if you give soymilk to women in Texas? Circulating estrogen levels cut in half. Since increased estrogen levels are a “[marker] for high risk for breast cancer,” the effectiveness of soy to reduce estrogen levels may help explain why Chinese and Japanese women have such low rates of breast cancer.

And, what was truly remarkable is that estrogen levels stayed down a month or two, even after they stopped drinking it. This suggests you don’t have to consume soy every day to have the cancer-protective benefit.

Doctor’s Note

Wait, soy protects against breast cancer? Yes, in study after study after study. Even in women at high risk? See BRCA Breast Cancer Genes & Soy.

Even if you already have breast cancer? See Is Soy Healthy for Breast Cancer Survivors?

Even GMO soy? See GMO Soy & Breast Cancer.

Okay, then, Who Shouldn’t Eat Soy? Watch that video too! 🙂

What else can we do to decrease breast cancer risk? See:

If you haven’t yet, you can subscribe to my videos for free by clicking here.

In health,
Michael Greger, M.D.

Michael Greger, M.D., is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United

How To Have A High Calorie Healthy Breakfast (Dairy & Sugar Free)

How to have over a 1,000 calories for breakfast and feel great!! Before taking your morning walk or beginning your exercise routine try the following:

Before Exercise Routine:

  • 1 banana
  • 2 apples

Slice organic fruit and eat.

After Exercise Routine:

  • 1 mango
  • 2 bananas
  • 2 tbs chia seeds
  • 1 cup almond milk

Blend all organic ingredients together and drink.

It’s just 10 am and I have tons of great energy and a big smile on my face!

Enjoy!

To get more of these great recipes visit Neeva’s website  The Innergy

 

How Much Soy Should You Eat To Lower Breast Cancer Risk?

So, we know 7 to 18 servings of soy a day may neutralize some of the beneficial effects of avoiding animal protein. At the same time, studies have repeatedly found that women who eat lots of soy appear to have a lower risk of getting breast cancer, and a better risk of surviving breast cancer than those who don’t eat soy. So is there some magic number of soy food servings we should shoot for?

So far we know that somewhere between 7 and 18 may not be so good, so more than 18 definitely gets the axe. This two year study found no effect on IGF levels of adding two servings of soy foods daily, whether they were tofu, soy milk, soy nuts, or the concentrated soy isolate found in plant-based meats, protein bars, or protein powder; still fine.

Still got a big range here. This study suggested 5 to 10 servings a day was bad— increased IGF—so we’re kind of slowly but surely narrowing down the safety window. Same year in Japan; three servings a day cleared the IGF radar. And then, that’s it. That’s all the science we have so far.

The bottom line is that legumes should be a part of everyone’s daily diet, which means lentils, peas, and/or beans, ideally with each of our meals—of which soy is an excellent choice. But, I recommend that we should probably stick to no more than 3 to 5 servings a day.

Doctor’s Notes

This is the fourth in a string of videos on the role plant and animal proteins play in determining levels of the cancer-promoting growth hormone IGF-1. Also see IGF-1 as One-Stop Cancer ShopProtein Intake and IGF-1 ProductionHigher Quality May Mean Higher RiskAnimalistic Plant Proteins; and Too Much Soy May Neutralize Benefits. For the role soy plays in extending breast cancer survival, see Breast Cancer Survival and Soy. And, I’ve got dozens of other videos on soy.

For further context, be sure to check out my associated blog posts: How Much Soy Is Too Much? and Why Less Breast Cancer in Asia?

If you haven’t yet, you can subscribe to my videos for free by clicking here.

In health,
Michael Greger, M.D.

Michael Greger, M.D., is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United

BRCA Breast Cancer Genes & Soy Consumption Research Results

Why do people who eat legumes—beans, chickpeas, split peas, and lentils—live longer? Well, men and women who eat legumes tended towards being lighter, having a slimmer waist, lower blood sugars, lower cholesterol, lower triglycerides, better kidney function, lower blood pressure, and so—no surprise—may live longer. But, interestingly, bean intake was “a better protectant against mortality in women than men.” They think this may be because cancer was the leading killer of women in this population—especially breast cancer. And, we know that breast cancer survivors who eat soy foods, for example, have a significantly lower likelihood of the cancer recurrence. Eating soy foods appears to protect against the cancer coming back. This 2012 review looked at three prospective human studies done to date, and found that women who ate the most soy had a 29% lower risk of dying from breast cancer, and a 36% lower risk of cancer recurrence. And, a fourth study was since published, and it showed the same thing. “[S]oy food intake is associated with longer survival and lower recurrence among breast cancer patients. With an average intake of soy phytonutrients above 17 milligrams a day, which is about what’s found in a single cup of soy milk, the mortality of breast cancer may be able to be reduced by as much as 38%.

Here’s the survival curve over five years. The purple line represents the survival of the women with the highest soy consumption. As you can see, after two years, all the breast cancer survivors eating lots of soy were still alive. But, a quarter to a third of the women who ate the least soy were dead. And, after five years, 90% of the tofu-lovers were still alive and kicking, whereas half of the tofu-haters kicked the bucket. And, you can see a similar relationship when you look at breast cancer survival and soy protein intake, as opposed to soy phytonutrient intake.

How does soy so dramatically decrease cancer risk, and improve survival? Soy may actually help turn back on BRCA genes. BRCA is a so-called caretaker gene, an oncosuppressor—meaning a cancer-suppressing gene responsible for DNA repair. Mutations in this gene can cause a rare form of hereditary breast cancer, popularized by Angelina Jolie’s public decision to undergo a preventive double mastectomy.

But, only about 5% of breast cancers run in families. So, 95% of breast cancer victims have fully functional BRCA genes. So, if their DNA-repair mechanisms are intact, how did breast cancer form, grow, and spread? Well, tumors do it by suppressing the expression of the gene, through a process called methylation. The gene’s fine, but cancer found a way to turn it off, or at least turn it down—potentially facilitating the metastatic spread of the tumor.

And, that’s where soy may come in. Maybe the reason soy intake is associated with increased survival and decreased cancer recurrence is because the phytonutrients in soy turn back on your BRCA protection—removing the methyl straightjacket the tumor tried to place on it.

So, researchers put it to the test. These are three different types of human breast cancer, specially stained so that the expression of BRCA genes turns up brown. So, this is what full DNA repair would look like—hopefully, what normal breast cells would look like. Lots of brown, lots of BRCA expression. But, instead, we have column two, raging breast cancer.

Well, if you add soy phytonutrients back to the cancer, BRCA does indeed get turned back on. The DNA repair appears to start ramping back up—though this was at a pretty hefty dose, equivalent to about a cup of soybeans.

Their results suggest that treatment with soy phytonutrients “might reverse DNA hypermethylation, and restore the expression” of the tumor-suppressor genes BRCA1 and BRCA2. May help with other breast cancer genes, as well. “Women at increased [genetic] risk of breast cancer may especially benefit from high [soy] intake.”

Doctor’s Notes

Legumes leading to a longer life? See Increased Lifespan from Beans.

No matter what genes we inherit, changes in diet can affect DNA expression at a genetic level. For example, see:

I’ve previously covered the available science in Breast Cancer Survival & Soy. Other effects are detailed in:

It may be possible to overdo beans, though (see How Much Soy Is Too Much?).

For further context, check out my associated blog posts: Top 10 Most Popular Videos of 2013 and Can Eating Soy Prevent Breast Cancer?

If you haven’t yet, you can subscribe to my videos for free by clicking here.

In health,
Michael Greger, M.D.

Michael Greger, M.D., is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United

Delicious & Healthy Lentil Tomato Soup For A Cancer Diet

This soup will be wonderful only if you will use ripe tomatoes that taste great, as they make the difference between good soup and an amazing one! Always use organic ingredients when possible.

Try this Rye Bread Recipe to make a complete and delicious meal.

What you need:

2 large sweet potatoes, peeled and sliced 
3 small potatoes, peeled and sliced 
3 large ripe tomatoes, cut to cubes
Handful of chopped coriander 
1 small onion, peeled and chopped
1 cup red lentils
Filtered water to cover
2 spoons avocado oil

What to do:

  1. Use a wide pot to saute the onion in the avocado oil until golden.
  2. Add the rest of the ingredients and add water to cover.
  3. Bring to boil and then continue cooking on a low heat until the potatoes are soft (about 30 minutes).
  4. When ready, you may use a hand blender to mix the soup; it’s great to only mix half so you still have some chunks of veggies in each plate.

Enjoy!

To get more of these great recipes visit Neeva’s website  The Innergy

Visit: www.NeverMeatAgain.com

Delicious Tempura Mushrooms – Vegan and Crispy

Another delicious way to enjoy mushrooms – and so much healthier than any tempura you buy!

What you need:

  • 10-15 fresh button mushrooms, cut to halves
  • 7 spoons rice flour (placed in a bowl or plate)
  • 1/2 cup reduced sodium soy sauce (placed in a bowl)
  • Avocado oil to stir-fry
  • Always use organic ingredients when possible

What to do:

  1. Heat the oil in a wide pan until it’s very hot.
  2. Dip the mushrooms in the soy sauce and then coat them with the rice flour.
  3. Stir-fry the mushrooms in the oil from both sides until they are soft from the inside and crispy from the outside.

You may eat the mushrooms by itself or add them to a salad. It’s best to eat them hot.

Enjoy!

To get more of these great recipes visit Neeva’s website  The Innergy

Visit: www.NeverMeatAgain.com

Should Women at High Risk for Breast Cancer Avoid Soy?

Five studies have been performed on breast cancer survival and soy foods, involving more than 10,000 breast cancer patients. And, those who eat more soy live longer, and have a lower risk of the cancer coming back. But, what about women who carry breast cancer genes? Fewer than 10% of breast cancer cases run in families. But, when they do, it’s most likely mutations to one of the tumor suppressor genes—BRCA1 or BRCA2—that defend the integrity of our genes. They are involved in DNA repair, and so, if either one of them is damaged, or has mutations, chromosomal abnormalities can result, which can set us up for cancer.

This idea that we have tumor suppressor genes goes back to famous research in the 60s that showed that if you fuse together a normal cell with a cancer cell, the cancer cell doesn’t turn the normal cell malignant. Rather, the normal cell suppresses the cancerous one. Tumor suppressor genes are typically split up into two types. There are gatekeeper genes that keep cancer cells in check, and caretaker genes that keep the cell from going cancerous in the first place. And, BRCA genes appear able to do both—that’s why their function is so important.

breast-cancer-and-soy-concernsUntil recently, dietary recommendations for those with mutations focused on reducing DNA damage caused by free radicals, by eating lots of antioxidant-packed fruits and vegetables. If your DNA-repair capacity is low, you want to be extra careful about damaging your DNA in the first place. But, what if we could also boost BRCA function?

In my last video on the topic, I showed how, in vitro, soy phytoestrogens could turn back on BRCA protection suppressed by breast cancer, upregulating BRCA expression as much as 1,000% within 48 hours. But, does that translate out of the petri dish and into the person? Apparently so.

Soy intake was only associated with 27% breast cancer risk reduction in people with normal BRCA genes, but a 73% risk reduction in carriers of BRCA gene mutations. So, a healthy diet may be particularly important in those at high genetic risk. Meat consumption, for example, was linked to twice as much risk in those with BRCA mutations—97% increased risk, instead of just 41% increased risk of breast cancer in those with normal BRCA genes.

Doctor’s Note

What about for women without breast cancer genes, or for women who have already been diagnosed? That was the subject of my last video, Is Soy Healthy for Breast Cancer Survivors?. The older video I referred to is BRCA Breast Cancer Genes & Soy.

What is in meat that may increase risk? See, for example:

Featured Image From Authority Nutrition and Livestrong.

In health,

Michael Greger, M.D.

Michael Greger, M.D., is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United

How to Make Stevia Extract to Reduce Your Sugar Intake

how-to-make-stevia-extractI’ve shied away from stevia in the past, because I hate its aftertaste. But, if you are trying to reduce your sugar intake, it is probably your best option of sweetener to use. So how can we make it more palatable? Today I’ll show you how to make your own stevia extract that doesn’t have a horrid aftertaste.

Years ago, I went to a cooking class on gluten-free and sugar-free baking. It was the worst cooking class I have ever attended – for various reasons! It was a demonstration, and the foods that were prepared were very high in refined carbohydrates (albeit gluten free ones) and fats. But no sugar – they used stevia instead. When we got to taste the dishes – I hated them all! I think that was the first time I had ever had stevia – and that aftertaste just wouldn’t go away.

But today, after some investigation, I am a little more tolerant of stevia. You can reduce or avoid its aftertaste,which makes stevia a good option to help you transition to avoiding sugar and other artificial sweeteners.

Stevia comes from the leaves of a plant called Stevia rebaudiana, and is usually found as a powder or a liquid extract. The active compounds of stevia are steviol glycoside – which has 150 times the sweetness of sugar. Stevia does not affect blood glucose levels, and some studies show it may help improve insulin sensitivity.

What I have found is that the bitter aftertaste is apparent when too high a concentration of stevia is used. Even though recipes with stevia call for just a few drops – if the extract or powder is really concentrated, that can still be too much. So taking it easy is the way to go.

To make stevia powder, collect stevia leaves and dry them, then finely chop them in a blender. The dried leaf powder can be used as is, in certain recipes – but they won’t dissolve, so don’t try them in your coffee!

There are many different ways to prepare an extract, with variables including:

  • using fresh leaves or dried leaves

    I use fresh leaves that I grow myself. They are easy to grow, and the plant regrows every year. The ideal time to harvest the leaves is around August – when the flowers start to appear but before the flowers start dying. If you leave it too late, you are more likely to get bitterness. If you can’t get fresh leaves, you can buy the dried leaves and use them instead.

  • with alcohol or  without alcohol

    I use alcohol – vodka – for my extract, because it extracts the sweetness well, and quickly. Any recipe calls for only a few drops of extract, which means there is negligible alcohol in the final product.

  • duration of the extraction time

    I extract for a relatively short period because, again, I find that the sweetness comes through quickly, and there is more likely to be an aftertaste if you leave the leaves in the alcohol for a longer period.

  • concentrating the extract by heating

    I choose not to heat the extract and reduce it as I don’t want it to be highly concentrated. By leaving the extract as it is, the amount you put into a recipe is more controllable. Yes, maybe I’ll use 6 drops instead of 2, but I can taste it as I go along and adjust the sweetness to how I want it.

Obviously, you can adjust these to your own taste. Here’s the recipe. I hope you’ll give it a try. If you live near me and want some leaves – just let me know.H

Homemade stevia extract:

Ingredients

  • Fresh stevia leaves
  • Unflavored vodka
  • (you can vary the amount as you wish – for proportions, see the recipe).

Instructions

  1. Wash the stevia leaves
  2. Roughly tear the leaves into a couple of pieces and place them in a clean jar. I filled the jar with leaves – but they weren’t compressed down.
  3. Add enough vodka to cover the leaves. For my jar, this was about half full as the liquid compresses the leaves.
  4. Seal and shake the jar.
  5. Leave for 8-12 hours. Taste the liquid to see if it is sweet enough.
  6. Strain the liquid into a bottle and discard the leaves.
  7. Keep the bottle in the dark, or use a brown colored bottle. Having a dropper helps, as only a few drop are needed to sweeten foods.
Recipe Type: Sugar-free, gluten free, vegan, paleo, sugar substitute

Notes:

If you prefer a more concentrated extract, you can gently simmer the extract to boil off some of the alcohol.

Ruth BaillieRuth Baillie is originally from the UK and now lives most of the year in Northern California. She holds two Master’s degrees, one in Personalized Nutrition (distinction), and another in Health Psychology. She is a Registered Nutritional Therapist, Certified Professional Cancer Coach, and Cancer Guide, and has undertaken considerable post-graduate studies in integrative naturopathic oncology. She is the author of “Choices in mind-body medicine for cancer patients in Sonoma County, California” and her research has been published in peer-reviewed journals.

Prevent Breast Cancer With These 5 Healthy Lifestyle Choices

Healthy Lifestyle Choices To Prevent CancerNecessary Lifestyle Choices for Optimum Health
An anti-cancer lifestyle will include a variety of exercise, organic foods, clean pure water and air. There are a few easy steps to keep the body safe and healthy. It is important to cultivate an awareness of what feels and taste right going into your body. It is equally important to stop and take notice of bad choices. Ask yourself “Is this good or bad for me? “Will it make me feel better or worse?” We all want to feel alive and vital.

1. Exercise – Yoga
Practicing restorative yoga has shown through studies to encourage and improve sleep and to enhance overall quality of life. (Reuters Health) – About one third of breast cancer survivors experience fatigue that affects their quality of life. A new study found that doing yoga might help restore some lost vitality. (bit.ly/sSZeZZ)

There are some simple suggestions to start exploring a change in vitality:

2. Cancer Prevention Foods – Vegetarian/Vegan Diet
It is suggested to eat a plant base diet of fruits and vegetables: make your diet rich in organic fruits and vegetables that are full of micronutrients and bioflavonoids which are duly noted to help prevent breast cancer or other cancers. Five or more servings per day is recommended by the American Cancer Institute. Red and blue berries hold a significant amount of necessary cell builders and anti-cancinogens that are a necessity on our tables.

Here are some simple choices to select from to start improving your health:

3. Water Therapy – Alkaline Water
Alkaline water (referred to as ionized water) can neutralize or decrease the acidity of the body’s pH caused by stress, modern diet, and air pollution. We suggest trying this water and feeling the possible positive effects.

Find a water store and get alkaline water by the gallon (it usually stays charged with negative ions for up to 48hours)
Purchase if possible a home alkaline water system that filters pollutants as well as charging the water with negative ions and anti oxidants

  • Benefit from the many ways to use alkaline water like necessary hydration for the body’s cells

4. Manage Stress – Learn to breathe
Deep breathing is vital in that it encourages the release of body toxins, rebuild healthy tissue which consequently increases overall energy. This true oxygen exchange stimulates digestion, assimilation and elimination. A very important function of breathing fully and slowly is that the body’s natural relaxation response is prompted. This relaxation response results in decreased tension, anxiety and fatigue.

A great place to start is with our single down-loadable breathing exercises or you could do the following.

5. Laugh Often – Emotional Balancing
It has been shown that even when manipulated to smile people in truth feel happier and joyful. Laughter can stop depression right in its tracks and boosts our immunity.

We suggest the following to bring on happiness.

  • Have a daily joke sent to your e-mail
  • Watch funny YouTube videos
  • Listen to the comedy channel on the radio
  • Download comedians from iTunes
Dawn Breast CancerAbout Dawn Bradford Lange:  Co-founder of Breast Cancer Yoga. Dawn is making a difference with Breast Cancer Yoga therapeutic products designed to support you emotionally and physically during breast cancer . We want to give you the attention and personal service you need so please email us atinfo@breastcanceryoga.com if you have questions.

Is Soy Healthy for Breast Cancer Survivors?

is-soy-healthy-for-breast-cancer-survivorsSoyfoods have become controversial in recent years,…even among health professionals,…exacerbated by misinformation found on the Internet.” Chief among the misconceptions is that soy foods promote breast cancer, because they contain a class of  phytoestrogen compounds called isoflavones. Since estrogens can promote breast cancer growth, it’s natural to assume phytoestrogens might too.

But, people don’t realize there are two types of estrogen receptors in the body—alpha and beta. And, unlike actual estrogen, soy phytoestrogens “preferentially bind to and activate [estrogen receptor beta]. This distinction is important, because the 2 [types of receptors] have different tissue distributions…and often function differently, and sometimes in opposite ways.” And, this appears to be the case in the breast, where beta activation has an anti-estrogenic effect, inhibiting the growth-promoting effects of actual estrogen—something we’ve known for more than ten years. There’s no excuse anymore.

The effects of estradiol, the primary human estrogen, on breast cells are completely opposite to those of soy phytoestrogens, which have antiproliferative effects on breast cancer cells, even at the low concentrations one gets in one’s bloodstream eating just a few servings of soy—which makes sense, given that after eating a cup of soybeans, the levels in our blood cause significant beta receptor activation.

So, where did this outdated notion that soy could increase breast cancer risk come from? The concern was “based largely on research that showed that [the main soy phytoestrogen] genistein stimulates the growth of mammary tumors in [a type of] mouse.” But, it turns out, we’re not actually mice. We metabolize soy isoflavones very differently from rodents. The same soy leads to 20 to 150 times higher levels in the bloodstream of rodents. The breast cancer mouse in question was 58 times higher. So, if you ate 58 cups of soybeans a day, you could get some significant alpha activation, too. But, thankfully, we’re not hairless athymic ovariectomized mice, and we don’t tend to eat 58 cups of soybeans a day.

At just a few servings of soy a day, with the excess beta activation, we would assume soy would actively help prevent breast cancer. And, indeed, “[s]oy intake during childhood, adolescence, and adult life were each associated with a decreased risk of breast cancer.” Those women who ate the most soy in their youth appear to grow up to have less than half the risk.

This may help explain why breast cancer rates are so much higher here than in Asia—yet, when Asians come over to the U.S. to start eating and living like Americans, their risk shoots right up.  For example, women in Connecticut—way at the top of the breast cancer risk heap—in their fifties have, like, ten times more breast cancer than women in their fifties living in Japan. But, it’s not just genetic, since when they move here, their breast cancer rates go up generation after generation, as they assimilate into our culture.

Are the anti-estrogenic effects of soy foods enough to actually change the course of the disease? We didn’t know, until the first human study on soy food intake and breast cancer survival was published in 2009 in the Journal of the American Medical Association, suggesting that “[a]mong women with breast cancer, soy food consumption was significantly associated with decreased risk of death and [breast cancer] recurrence.” Followed by another study, and then another, all with similar findings.

That was enough for the American Cancer Society, who brought together a wide range of cancer experts to offer nutrition guidelines for cancer survivors, to conclude that, if anything, soy foods should be beneficial. Since then, two additional studies have been published, for a total of five, and they all point in the same direction. Five out of five, tracking more than 10,000 breast cancer patients.

Pooling all the results, soy food intake after breast cancer diagnosis was associated with reduced mortality (meaning a longer lifespan) and reduced recurrence—so, less likely the cancer comes back. Anyone who says otherwise hasn’t cracked a journal open in seven years.

And, this improved survival was for both women with estrogen receptor negative tumors and estrogen receptor positive tumors, and for both younger women, and for older women. Pass the edamame.

Doctor’s Note

This is probably the same reason flax seeds are so protective. See Flax Seeds & Breast Cancer Survival: Epidemiological Evidence and Flax Seeds & Breast Cancer Survival: Clinical Evidence.

What about women who carry breast cancer genes? I touched on that in BRCA Breast Cancer Genes & Soy, and it’s the topic of my next video, Should Women at High Risk for Breast Cancer Avoid Soy?

What about genetically modified soy? I made a video abut that too; see GMO Soy & Breast Cancer.

Who Shouldn’t Eat Soy? Glad you asked. Watch that video too! 🙂

Not all phytoestrogens may be protective, though. See The Most Potent Phytoestrogen is in Beer and What are the Effects of the Hops Phytoestrogen in Beer?

In health,

Michael Greger, M.D.

Michael Greger, M.D., is a physician, New York Times bestselling author, and internationally recognized professional speaker on a number of important public health issues. Dr. Greger has lectured at the Conference on World Affairs, the National Institutes of Health, and the International Bird Flu Summit, testified before Congress, appeared on The Dr. Oz Show and The Colbert Report, and was invited as an expert witness in defense of Oprah Winfrey at the infamous “meat defamation” trial. Currently Dr. Greger proudly serves as the Director of Public Health and Animal Agriculture at the Humane Society of the United

%d bloggers like this: