Vitamin C therapy is proven to have positive effects in treating cancer. It can also be used to enhance the effects of chemotherapy and radiotherapy. Learn more about Vitamin C therapy in the article below.
What is i.v. Vitamin C Therapy?
Vitamin C therapy is a high dose of Vitamin C given intravenously (i.v.). Vitamin C therapy is not new; however prior studies focused on it being given orally. I/V vitamin C is way more different than the oral form in its application. High doses of I/V vitamin C have unique application as a therapeutic tool in cancer management as they can reach a higher concentration in blood than the oral form. Studies suggest that vitamin C in higher doses can cause the death of cancer cells
How does i/v Vitamin C Work?
For Vitamin C to work effectively against cancer cells, it must be given through i.v. route. Additionally, it must be given in high doses for it to generate hydrogen peroxide. Hydrogen peroxide forms on the interaction of vitamin C with iron and other metals.
Hydrogen peroxide is lethal to cancer cells, in increased amounts as it causes the damage to the DNA and the mitochondria of cancer cells. Thus destroying them by limiting their energy supply. The high doses have a pro-oxidant effect rather than an anti-oxidant one.It oxidizes the tissues by converting the free radicles into hydrogen peroxide that can destroy the cancer cells if not neutralized by an enzyme in the cells called catalase.
Current research suggests that vitamin C concentration above 1000micromol/l reached after an I/V dose is toxic to some cancer cells. Experiments showed that lipoic acid further boost the anticancer activity of high-dose I/V vitamin C. Researchers suggests that vitamin C also prevent the action of proteins that results in slow growth of the tumor along with decreased formation of new blood vessels(angiogenesis).
Physicians have the ability to provide i.v. Vitamin C treatments within a clinical setting.
Advantages of i.v. Vitamin C with Different Types of Cancer
Research shows that Vitamin C used intravenously may benefit patients with poor prognosis, those with minimal treatment options, or those whose cancer has reached an advanced status.
Vitamin C intravenously may reduce tumor size in some patients.
Patients with ovarian cancer may respond positively to Vitamin C when used in conjunction with other antioxidants.
Vitamin C intravenously may also be beneficial for patients with lung cancer, lymphomas or metastatic cancers.
Researchers at Kansas University have reported that Vitamin C injected directly into the ovarian cancer cells in humans and mouse helps in the death of these cells leaving intact the normal cells.
Laboratory studies have shown that I/V vitamin therapy is beneficial in the treatment of several different cancer types that include lung, brain, breast, colon, pancreatic and ovarian cancer.
What is the Effect of i.v. Vitamin C on Metastasis?
Some research suggests that Vitamin C in higher doses given intravenously may lead to tumor regression.
Does i/v Vitamin C Enhance the Effect of Chemotherapy?
It is suggested that I/V vitamin C therapy should be given in combination with other therapies such as chemotherapy due to its synergistic effects. Research has shown that antioxidants, including Vitamin C, may improve the effectiveness of chemotherapy. Evidence proves that higher concentrations of vitamin C in the blood and tissues can reduce the toxicity or increase the efficacy of chemotherapy.
Does i/v Vitamin C Enhance the Effects of Radiation?
Intravenous Vitamin C may cause improvement in the effectiveness of radiation therapy.
Can i.v. Vitamin C-Reduce the Side Effects of Chemotherapy and Radiation?
Using Vitamin C intravenously has shown to result in a decrease of nausea, fatigue, depression, sleep disorders, loss of appetite and hemorrhagic diathesis.
What Influence does i/v vitamin c have on the Immune System?
Vitamin C has many benefits than cancer killing. It also works by stimulating the immune system and decreasing the risk of infections and other diseases. The immune system responds positively to Vitamin C, as it is a needed requirement to rebuild cells and restore depleted nutrients. High doses of Vitamin C also allow the body to absorb iron.
Does i/v? Vitamin C Increase Quality of life and Survival Rate?
The use of high dose I/V vitamin in increasing the life span of cancer patients was first proposed by Linus Pauling and Ewan Cameron in 1976. 
Using Vitamin C intravenously can increase the quality of life by decreasing cancer treatment-related side-effects.Vitamin C may also increase the quality of life in late-stage cancer patients.
Terminally ill patients with cancer may experience prolonged life after treatment with intravenous Vitamin C.
Vitamin C is imperative for the healthy functioning of the human body. There is a plethora of research that shows how using Vitamin C intravenously may or may not have positive impacts on patients with cancer.
Oral doses of Vitamin C have not been shown to have clinical significance in the treatment of cancer. Vitamin C is given intravenously in higher doses to reduce tumor growth and enhance the effects of radiation and chemotherapy.
It is noticed that some research has shown positive results from Vitamin C used intravenously in conjunction with other antioxidants in cancer care. Studies have also failed to show any negative side effects from using Vitamin C intravenously except mild tiredness and occasional gastric trouble with high doses.
There is continuous research going on to explore further about the role high dose I/V vitamin C therapy in cancer care. It is expected tat shortly I/V vitamin C therapy might emerge as a miraculous drug in the treatment of cancer. It is suggested to follow the recent recommendations and take I/V vitamin C therapy under the supervision of your doctor.
-  Riordan NH, Riordan HD, Meng X, Li Y, Jackson JA. Intravenous ascorbate as a tumor cytotoxic chemotherapeutic agent. Med Hypotheses. 1995;44(3):207-213.
-  Park JH, Davis KR, Lee G, Jung M, Jung Y, Park J, Yi SY, Lee MA, Lee S, Yeom CH, Kim J. Ascorbic acid alleviates toxicity of paclitaxel without interfering with the anticancer efficacy in mice.Nutr Res. 2012 Nov; 32(11):873-83.
-  Cameron E, Pauling L (October 1976).“Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancer”. PNAS 73 (10): 3685-3689. Bibcode:1976PNAS…73.3685C. doi:10.1073/pnas.73.10.3685. PMC 431183.PMID 1068480.
Featured Photo: Foundation for Alternative and Integrative Medicine
Dr. Adem Gunes has built the world’s largest database of scientifically tested natural substances with proven effects in cancer treatments. In 2009, he was appointed as the Chief Physician of ProLife Clinic in Innsbruck, Austria, and played a key role in the establishment of the research laboratory. He is also the co-founder of the first Austrian hyperthermia center. Now, Dr. Adem works closely with cancer patients from around the world (including Germany, Thailand, Dubai) to recommend them a complementary cancer clinic or to create a personalized care plan for patients to follow at home.