Ginger and Breast Cancer
A recent study performed by researchers in the Biological Sciences Department, Faculty of Sciences at the King Abdul Aziz University in Saudi Arabia suggests that the crude extract obtained from ginger plants (also known as Zingiber officinale), causes the inhibition of cellular proliferation in breast cancer without causing any harm to the normal cells.
According to the latest research published in the Journal of Biomedicine and Biotechnology, ginger is a favorable option in the treatment of breast carcinomas. This property is referred to as selective toxicity, and it is not present in the conventional treatment options.
The researchers have highlighted a significant issue that suggests that despite the recent advancement in the cancer treatment, breast cancer continues to be the commonest cancer in women and the leading cause of cancer deaths. Furthermore, it is also considered that breast cancer cells can develop resistance to treatment at some point. Therefore, it is highly desirable to discover newer agents that provide the growth suppression of both ER-positive and ER-negative breast cancers without causing potential side effects.
Researchers have stated that ginger is considered a powerful anticancer compound but the molecular mechanism responsible for its anti-cancer activity are still to be discovered. Depending on the older scientific records and considering the fact that herbal extracts are more effective than the purified components, a study was conducted to find out the effect of crude extract of ginger on the growth of cell lines of breast cancer.
Ginger is provided with the unique ability of positively regulating a variety of molecular mechanisms at the same time which include:
- Inducing apoptosis that is the programmed death of cells
- Up-regulating certain pro-apoptotic and anti-cancer genes such as Bax, p21, CDK inhibitor
- Downregulating certain cancer-associated proteins and genes such as Bcl-2, NF-kb, Bcl-X, Mcl-1, CDK-4, C-Myc, hTERT, etc.
Apart from this, recent studies have also shown that there is also compound ginger called Gingerol which is found to have some anti-metastatic activities in the treatment of breast cancer.
The anti-cancer effect of ginger is not only limited to breast cancer, but its components are known to cause the inhibition of the lung cancer, liver cancer, colorectal cancer, prostate cancer, pancreatic cancer and melanoma.
Ginger is considered a type of food that provides us with nutrition along with relieving the pain and disease. Nowadays it is used as a spice, food ingredient as well as in medicine by different cultures all over the world. It is suggested through modern research that ginger is associated with over hundred different health benefits.
It is believed that ginger was first originated in southern China thousands of years ago from there it is distributed to other parts of the world including Asia, West Africa, Caribbean and at the end India. India has now reached the status of the largest ginger producer. Recent evidence also suggests that Greece was also involved in the trade of ginger dating back to the 3rd century BC.
Dr. Adem Gunes has built the world’s largest database of scientifically tested natural substances with proven effects in cancer treatments. In 2009, he was appointed as the Chief Physician of ProLife Clinic in Innsbruck, Austria, and played a key role in the establishment of the research laboratory. He is also the co-founder of the first Austrian hyperthermia center. Now, Dr. Adem works closely with cancer patients from around the world (including Germany, Thailand, Dubai) to recommend them a complementary cancer clinic or to create a personalized care plan for patients to follow at home.